Tg(Prox1-cre/ERT2)1Jscal
Transgene Detail

Summary

• Symbol: Tg(Prox1-cre/ERT2)1Jscal
• Name: transgene insertion 1, Joshua Scallan
• MGI ID: MGI:7537333
• Synonyms: Prox1CreERT2
• Transgene: Tg(Prox1-cre/ERT2)1Jscal Location: unknown
• Alliance: Tg(Prox1-cre/ERT2)1Jscal page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Prox1-cre/ERT2)1Jscal expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prox1 (MGI:97772)

• Mutation details: The RP23-360I16 BAC clone was used to generate a transgene in which CreERT2 followed by an SV40 polyA stop sequence was inserted after the start codon in exon 2 of the Prox1 gene. Random transgenesis generated 4 founders and the highest efficiency founder (line1) was selected for propagation. (J:341378)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prox1 (mouse) Summary of all recombinase alleles driven by Prox1. Alliance mouse Prox1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:341378 Iyer D, et al., eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice. Arterioscler Thromb Vasc Biol. 2023 Sep 28
• All: 3 reference(s)