Gt(ROSA)26Sor^{em1(FOXM1)Jwji}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(FOXM1)Jwji}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Jianwei Jiao
• MGI ID: MGI:7537021
• Synonyms: hFOXM1^flox
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(FOXM1)Jwji} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{em1(FOXM1)Jwji} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FOXM1 (2305)

  Foxm1

  (MGI:1347487)

• Mutation details: Using CRISPR/Cas9 system, the sequence containing CAG-loxP-Stop-hFOXM1-3flag-WPRE-PA was inserted into the Rosa26 site between exon 1 and exon 2. (J:337816)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:337816 Wang W, et al., The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse. EMBO Rep. 2022 Feb 3;23(3):e53602
• All: 1 reference(s)