Baiap2^tm1.1Csbd
Targeted Allele Detail

Summary

• Symbol: Baiap2^tm1.1Csbd
• Name: brain-specific angiogenesis inhibitor 1-associated protein 2; targeted mutation 1.1, Eunjoon Kim
• MGI ID: MGI:7536957
• Synonyms: Irsp53^fl
• Gene: Baiap2 Location: Chr11:119833762-119897608 bp, + strand Genetic Position: Chr11, 83.96 cM, cytoband E2
• Alliance: Baiap2^tm1.1Csbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:290857
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A targeting vector is designed to contain (from 5' to 3') a frt site, an En2 splice acceptor, an internal ribosome entry site (IRES) fused to an EGFP sequence with a polyadenylation signal, and a floxed cassette containing a neo and a second frt site all upstream of exon 4. A third loxP was placed downstream of exon 6. Flp-mediated recombination removed the neo cassette and the 5' loxP site, leaving exons 4-6 floxed. (J:290857)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Baiap2 Mutation: 30 strains or lines available

References

• Original: J:290857 Kim Y, et al., IRSp53 Deletion in Glutamatergic and GABAergic Neurons and in Male and Female Mice Leads to Distinct Electrophysiological and Behavioral Phenotypes. Front Cell Neurosci. 2020;14:23
• All: 5 reference(s)