Npr1^em1Shche
Endonuclease-mediated Allele Detail

Summary

• Symbol: Npr1^em1Shche
• Name: natriuretic peptide receptor 1; endonuclease-mediated mutation 1, Shenghan Chen
• MGI ID: MGI:7536894
• Synonyms: Npr1^-
• Gene: Npr1 Location: Chr3:90357898-90373173 bp, - strand Genetic Position: Chr3, 39.23 cM
• Alliance: Npr1^em1Shche page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Mutation details: A null allele was generated using using CRISPR/Cas9 technique. No molecular description was provided. (J:338036)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npr1 Mutation: 58 strains or lines available

References

• Original: J:338036 Long C, et al., Null Function of Npr1 Disturbs Immune Response in Colonic Inflammation During Early Postnatal Stage. Inflammation. 2022 Dec;45(6):2419-2432
• All: 2 reference(s)