Ube2i^em1Hars
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ube2i^em1Hars
• Name: ubiquitin-conjugating enzyme E2I; endonuclease-mediated mutation 1, Sean M Hartig
• MGI ID: MGI:7532786
• Synonyms: Ube2i^fl
• Gene: Ube2i Location: Chr17:25479482-25493856 bp, - strand Genetic Position: Chr17, 12.53 cM
• Alliance: Ube2i^em1Hars page

Mutation origin

• Strain of Origin: C57BL/6NJ

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 mediated recombination using a pair of single guide RNAs inserted loxP sites around exons 3 and 4. (J:340724)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ube2i Mutation: 22 strains or lines available

References

• Original: J:340724 Cox AR, et al., Ube2i deletion in adipocytes causes lipoatrophy in mice. Mol Metab. 2021 Jun;48:101221
• All: 3 reference(s)