Ucp1em1(cre)Chez
Endonuclease-mediated Allele Detail
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Symbol: |
Ucp1em1(cre)Chez |
Name: |
uncoupling protein 1 (mitochondrial, proton carrier); endonuclease-mediated mutation 1, Zheng Chen |
MGI ID: |
MGI:7532766 |
Synonyms: |
Ucp1-iCre |
Gene: |
Ucp1 Location: Chr8:84016981-84025081 bp, + strand Genetic Position: Chr8, 39.65 cM
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Alliance: |
Ucp1em1(cre)Chez page
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Strain of Origin: |
Not Applicable
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Allele Type: |
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Endonuclease-mediated (Recombinase) |
Mutation: |
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Insertion
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Ucp1em1(cre)Chez expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Ucp1 (MGI:98894) |
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Mutation details: An IRES-Cre was introduced between the coding sequence of exon 6 and the 3'UTR of the Ucp1 gene. To avoid disrupting the polyA signal of Ucp1 expression, a Neo cassette flanked by frt sites was inserted 300 bp downstream of the 3'UTR.
(J:283206)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ucp1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ucp1 Mutation: |
46 strains or lines available
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Original: |
J:283206 Li L, et al., Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo. Mol Metab. 2017 Oct;6(10):1198-1211 |
All: |
3 reference(s) |
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