Cavin1^em1Klon
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cavin1^em1Klon
• Name: caveolae associated 1; endonuclease-mediated mutation 1, Karen Long
• MGI ID: MGI:7532697
• Synonyms: Ptrf KO
• Gene: Cavin1 Location: Chr11:100847562-100861443 bp, - strand Genetic Position: Chr11, 63.95 cM
• Alliance: Cavin1^em1Klon page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Using the CRISPR/Cas9 system, the 12187bp genomic sequence spanning a part of exon 1 to exon 2 of the Cavin1 was deleted. (J:341139)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cavin1 Mutation: 11 strains or lines available

References

• Original: J:341139 Li X, et al., Decoding the transcriptome of muscular dystrophy due to Ptrf deficiency using single-nucleus RNA sequencing. FASEB J. 2023 Jun;37(6):e22993
• All: 1 reference(s)