Igf1^tm1Ispgl
Targeted Allele Detail

Summary

• Symbol: Igf1^tm1Ispgl
• Name: insulin-like growth factor 1; targeted mutation 1, Ivo Spiegel
• MGI ID: MGI:7532530
• Synonyms: Igf1-E1 cKO
• Gene: Igf1 Location: Chr10:87694127-87772904 bp, + strand Genetic Position: Chr10, 43.7 cM
• Alliance: Igf1^tm1Ispgl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:341100
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• The exon1 is flanked by LoxP sites and additionally includes a Neo cassette flanked by Frt sites. (J:341100)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf1 Mutation: 25 strains or lines available

References

• Original: J:341100 Roethler O, et al., Single genomic enhancers drive experience-dependent GABAergic plasticity to maintain sensory processing in the adult cortex. Neuron. 2023 Sep 6;111(17):2693-2708.e8
• All: 1 reference(s)