Idh2^em1Ycxu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Idh2^em1Ycxu
• Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial; endonuclease-mediated mutation 1, Yancheng Xu
• MGI ID: MGI:7530922
• Synonyms: IDH2-flox
• Gene: Idh2 Location: Chr7:79744594-79765140 bp, - strand Genetic Position: Chr7, 45.43 cM
• Alliance: Idh2^em1Ycxu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 3 was flanked by loxP sites via CRISPR/Cas9 technology. (J:340748)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Idh2 Mutation: 146 strains or lines available

References

• Original: J:340748 Wang H, et al., Hepatic IDH2 regulates glycolysis and gluconeogenesis. Metabolism. 2023 Apr 11;143:155559
• All: 1 reference(s)