Rnls^em1Nwan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnls^em1Nwan
• Name: renalase, FAD-dependent amine oxidase; endonuclease-mediated mutation 1, Niansong Wang
• MGI ID: MGI:7530666
• Gene: Rnls Location: Chr19:33115147-33369665 bp, - strand Genetic Position: Chr19, 29.08 cM
• Alliance: Rnls^em1Nwan page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN technology generated a 2 bp deletion (CA) in exon 4. (J:340675)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnls Mutation: 23 strains or lines available

References

• Original: J:340675 Wang Y, et al., Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice. Front Cardiovasc Med. 2022;9:1061146
• All: 1 reference(s)