Tlr3^em1Geh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tlr3^em1Geh
• Name: toll-like receptor 3; endonuclease-mediated mutation 1, Gregg Homanics
• MGI ID: MGI:7529488
• Gene: Tlr3 Location: Chr8:45848702-45864112 bp, - strand Genetic Position: Chr8, 25.31 cM, cytoband B2
• Alliance: Tlr3^em1Geh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 endonuclease-mediated genome editing is used to insert loxP sites in introns 5 and 6. Tlr3 transcript Tlr3-201 (ENSMUST00000034056.12) was used as reference for the exon number and guide sequences. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tlr3 Mutation: 71 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)