Tg(MoMuLV-RET*C634R)121Mat
Transgene Detail

Summary

• Symbol: Tg(MoMuLV-RET*C634R)121Mat
• Name: transgene insertion 121, Masahide Takahashi
• MGI ID: MGI:7529087
• Synonyms: Tg(MoMuLV/RET-MEN2A)121Mat
• Transgene: Tg(MoMuLV-RET*C634R)121Mat Location: unknown
• Alliance: Tg(MoMuLV-RET*C634R)121Mat page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MoMuLV-RET*C634R)121Mat expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  RET (5979)

  Ret	(MGI:97902)

  C634R mutation

• Mutation details: The transgene contains the human c-Ret cDNA (MEN2A-type mutant), MoMuLV LTR, rat insulin poly A, and SV40 poly(A) signal. Line 121 has 22 copies of the transgene. (J:64785)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:64785 Kawai K, et al., Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation. Cancer Res. 2000 Sep 15;60(18):5254-60
• All: 1 reference(s)