Pdcd1^em1(cre)Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pdcd1^em1(cre)Cya
• Name: programmed cell death 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7526525
• Synonyms: Pdcd1-Cre
• Gene: Pdcd1 Location: Chr1:93966027-93980278 bp, - strand Genetic Position: Chr1, 47.47 cM
• Alliance: Pdcd1^em1(cre)Cya page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Pdcd1^em1(cre)Cya expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pdcd1 (MGI:104879)

• No molecular detail is provided. (J:339958)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdcd1 (mouse) Summary of all recombinase alleles driven by Pdcd1. Comparative matrix view of recombinase activities Alliance mouse Pdcd1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd1 Mutation: 97 strains or lines available

References

• Original: J:339958 Zhao J, et al., PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior. Neuron. 2023 Sep 6;111(17):2709-2726.e9
• All: 1 reference(s)