Mir146^em1Anu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir146^em1Anu
• Name: microRNA 146; endonuclease-mediated mutation 1, Australian National University
• MGI ID: MGI:7526273
• Synonyms: miR-146a^-
• Gene: Mir146 Location: Chr11:43265224-43265288 bp, - strand Genetic Position: Chr11, 25.68 cM
• Alliance: Mir146^em1Anu page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISRP/Cas9 technology deleted the entire microRNA gene. (J:340137)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir146 Mutation: 14 strains or lines available

References

• Original: J:340137 Zhao W, et al., microRNA-146a modulates behavioural activity, neuroinflammation, and oxidative stress in adult mice. Mol Cell Neurosci. 2023 Feb 1;124:103820
• All: 1 reference(s)