Yap1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Yap1^em1Cya
• Name: yes-associated protein 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7525749
• Synonyms: Yap1^flox
• Gene: Yap1 Location: Chr9:7932000-8004597 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Yap1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted loxP sites to generate a conditional allele. (J:340046)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yap1 Mutation: 40 strains or lines available

References

• Original: J:340046 Zhang J, et al., YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis. Front Immunol. 2022;13:884362
• All: 1 reference(s)