Mboat4^tm1Shi
Targeted Allele Detail

Summary

• Symbol: Mboat4^tm1Shi
• Name: membrane bound O-acyltransferase domain containing 4; targeted mutation 1, Shionogi and Company
• MGI ID: MGI:7525365
• Gene: Mboat4 Location: Chr8:34582184-34592336 bp, + strand Genetic Position: Chr8, 20.9 cM
• Alliance: Mboat4^tm1Shi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:339929
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon1 of the gene was replaced with a PGK-Neo cassette by homologous recombination. (J:339929)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mboat4 Mutation: 17 strains or lines available

References

• Original: J:339929 Kouno T, et al., Ghrelin O-acyltransferase knockout mice show resistance to obesity when fed high-sucrose diet. J Endocrinol. 2015;228(2):115-25
• All: 1 reference(s)