Aplf^tm1Okad
Targeted Allele Detail

Summary

• Symbol: Aplf^tm1Okad
• Name: aprataxin and PNKP like factor; targeted mutation 1, Hitoshi Okada
• MGI ID: MGI:7524704
• Gene: Aplf Location: Chr6:87605406-87649175 bp, - strand Genetic Position: Chr6, 38.52 cM
• Alliance: Aplf^tm1Okad page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:339876
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced exons 2 and 3 with a neomycin selection cassette. (J:339876)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aplf Mutation: 36 strains or lines available

References

• Original: J:339876 Tong KI, et al., Attenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model. Cell Death Dis. 2016;7(10):e2401
• All: 1 reference(s)