Glp1r^em2Hod
Endonuclease-mediated Allele Detail

Summary

• Symbol: Glp1r^em2Hod
• Name: glucagon-like peptide 1 receptor; endonuclease-mediated mutation 2, David Hodson
• MGI ID: MGI:7524570
• Synonyms: Glp1r^SNAP
• Gene: Glp1r Location: Chr17:31120841-31155484 bp, + strand Genetic Position: Chr17, 15.8 cM
• Alliance: Glp1r^em2Hod page

Mutation origin

• Strain of Origin: STOCK Gt(ROSA)26Sor^{tm1.1(CAG-cas9*,-EGFP)Fezh}/J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology inserted a SNAPf-tag enzyme self-label into exon 1 after the N-terminal signal sequence. (J:339846)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glp1r Mutation: 52 strains or lines available

References

• Original: J:339846 Ast J, et al., Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling. Nat Commun. 2023 Jan 18;14(1):301
• All: 2 reference(s)