Pard3^tm1.1Ptb
Targeted Allele Detail

Summary

• Symbol: Pard3^tm1.1Ptb
• Name: par-3 family cell polarity regulator; targeted mutation 1.1, Paul Brinkkoetter
• MGI ID: MGI:7522773
• Synonyms: Par3A^fl
• Gene: Pard3 Location: Chr8:127790643-128338767 bp, + strand Genetic Position: Chr8, 74.66 cM, cytoband E2
• Alliance: Pard3^tm1.1Ptb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280134
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and an frt-flanked neomycin selection cassette were inserted in intron 5, and a second loxP site and an F5-flanked puromycin selection cassette were inserted into intron 6. Recombinase activity removed both selection cassettes, leaving loxP sites flanking exon 6. (J:280134)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pard3 Mutation: 99 strains or lines available

References

• Original: J:280134 Koehler S, et al., Par3A is dispensable for the function of the glomerular filtration barrier of the kidney. Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F112-9
• All: 2 reference(s)