Usp11^em1Rch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp11^em1Rch
• Name: ubiquitin specific peptidase 11; endonuclease-mediated mutation 1, Ruey Chen
• MGI ID: MGI:7522342
• Synonyms: Usp11^f, Usp11-floxed
• Gene: Usp11 Location: ChrX:20570148-20586778 bp, + strand Genetic Position: ChrX, 16.2 cM
• Alliance: Usp11^em1Rch page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Two loxP sequences were inserted into introns 1 and 9 of the gene using CRISPR-Cas9 genome editing technology. (J:306221)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp11 Mutation: 20 strains or lines available

References

• Original: J:306221 Chiang SY, et al., Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization. Sci Adv. 2021 Feb;7(7)
• All: 1 reference(s)