Pld2^em1Yaka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pld2^em1Yaka
• Name: phospholipase D2; endonuclease-mediated mutation 1, Yasunori Kanaho
• MGI ID: MGI:7522222
• Gene: Pld2 Location: Chr11:70430890-70448936 bp, + strand Genetic Position: Chr11, 42.99 cM
• Alliance: Pld2^em1Yaka page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted most of the coding region. (J:339362)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pld2 Mutation: 47 strains or lines available

References

• Original: J:339362 Ngo Thai Bich V, et al., Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8(+) T lymphocyte proliferation. Sci Rep. 2018 Apr 19;8(1):6283
• All: 1 reference(s)