Tg(Rr445-Mecom)1Kmori
Transgene Detail

Summary

• Symbol: Tg(Rr445-Mecom)1Kmori
• Name: transgene insertion 1, Kazuhiro Morishita
• MGI ID: MGI:7520836
• Synonyms: Evi1-Tg, Tg(mCNE-mhsp68-mEvi1)1Kmori
• Transgene: Tg(Rr445-Mecom)1Kmori Location: unknown
• Alliance: Tg(Rr445-Mecom)1Kmori page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rr445-Mecom)1Kmori expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mecom (MGI:95457)

• Tg(Rr445-Mecom)1Kmori expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Runx1 (MGI:99852)

• Mutation details: The transgene contains the mouse Evi1 under the control of chimeric promoter, Runx1+24 mouse conserved noncoding element (mCNE) and mouse heatshock protein 68 minimal promoter. (J:339249)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:339249 Saito Y, et al., EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase. Haematologica. 2020 Aug;105(8):2118-2129
• All: 1 reference(s)