Tg(Col2a1-Cd80)1Skncu
Transgene Detail

Summary

• Symbol: Tg(Col2a1-Cd80)1Skncu
• Name: transgene insertion 1, Satoshi Kanazawa
• MGI ID: MGI:7518847
• Transgene: Tg(Col2a1-Cd80)1Skncu Location: unknown
• Alliance: Tg(Col2a1-Cd80)1Skncu page

Transgene origin

• Strain of Origin: (FVB/NJ x DBA/1J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col2a1-Cd80)1Skncu expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cd80 (MGI:101775)

• Tg(Col2a1-Cd80)1Skncu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Col2a1 (25412)

  Col2a1

  (MGI:88452)

• The rat promoter drives expression of the mouse gene. (J:115002)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:115002 Kanazawa S, et al., Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14465-70
• All: 2 reference(s)