Tg(Ins2-Tnf)1Pva
Transgene Detail

Summary

• Symbol: Tg(Ins2-Tnf)1Pva
• Name: transgene insertion 1, Pierre Vassalli
• MGI ID: MGI:7517047
• Transgene: Tg(Ins2-Tnf)1Pva Location: unknown
• Alliance: Tg(Ins2-Tnf)1Pva page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins2-Tnf)1Pva expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tnf (MGI:104798)

• Tg(Ins2-Tnf)1Pva expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Ins2 (24506)

  Ins2	(MGI:96573)

• The rat promoter drives expression of the mouse gene. (J:338881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:338881 Higuchi Y, et al., Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med. 1992;176(6):1719-31
• All: 1 reference(s)