Ift122^m1Kvand
Chemically induced Allele Detail

Summary

• Symbol: Ift122^m1Kvand
• Name: intraflagellar transport 122; mutation 1, Kathryn Anderson
• MGI ID: MGI:7516603
• Synonyms: Ift122^TR2
• Gene: Ift122 Location: Chr6:115830431-115903660 bp, + strand Genetic Position: Chr6, 53.72 cM
• Alliance: Ift122^m1Kvand page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU treatment induced a C-to-A (or T-to-A in C57BL/6J, BALB/cJ, A/J and WSB/EiJ strains, see SNP rs30016529) mutation at position GRCm39:chr6:115876490 resulting in a premature stop codon (TAA) at codon 575 in exon 15 in place of the tyrosine codon (TAC or TAT). (J:304031)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ift122 Mutation: 52 strains or lines available

References

• Original: J:304031 Brooks ER, et al., Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure. Elife. 2020 Oct 26;9:e60234
• All: 1 reference(s)