Gt(ROSA)26Sortm14.1(Thy1-dre)Maoh
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm14.1(Thy1-dre)Maoh |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 14.1, Masato Ohtsuka |
MGI ID: |
MGI:7516494 |
Synonyms: |
Thy1-Dre |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm14.1(Thy1-dre)Maoh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:303408
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Parent Cell Line: |
E14TG2a (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm14.1(Thy1-dre)Maoh expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Thy1 (MGI:98747) |
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Mutation details: Recombinase-mediated cassette exchange (RMCE) replaced the expression cassette between the JT15 and lox2272 sites of Gt(ROSA)26Sortm1Maoh with Thy1-Dre cassette. Flp-mediated recombination removed the extra sequence downstream of the Thy1-Dre in the construct flanked by FRT sites. Lines 1-3 are established exhibiting similar recombination activity patterns. This allele is an representative of all three lines.
(J:303408)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Thy1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
944 strains or lines available
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Original: |
J:303408 Tamura S, et al., Thy1 promoter activity in the Rosa26 locus in mice: lessons from Dre-rox conditional expression system. Exp Anim. 2020 Aug 5;69(3):287-294 |
All: |
1 reference(s) |
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