Dimt1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dimt1^em1(IMPC)J
• Name: DIM1 rRNA methyltransferase and ribosome maturation factor; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:7515012
• Gene: Dimt1 Location: Chr13:107083635-107096732 bp, + strand Genetic Position: Chr13, 58.06 cM, cytoband D1
• Alliance: Dimt1^em1(IMPC)J page
• IMPC: Dimt1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory using Cas9 and guides with spacer sequences GAGCAATCGGTTCTACTGGT and TTCTGGCAAGAAACACAGGG that targeted exon(s) ENSMUSE00000120070.4 ENSMUSE00000120072.4 ENSMUSE00000120073.4 ENSMUSE00000311714.4. This resulted in deletion(s) of 1536 bp (location: Chr13:107084959-107086494; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Dimt1 Mutation: 16 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)