Siah1a^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Siah1a^em1Cya
• Name: siah E3 ubiquitin protein ligase 1A; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7514578
• Synonyms: Siah1a^em1Cflox, Siah1a^f
• Gene: Siah1a Location: Chr8:87450635-87472562 bp, - strand Genetic Position: Chr8, 42.1 cM
• Alliance: Siah1a^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9-mediated recombination inserted loxP sites. (J:336555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Siah1a Mutation: 15 strains or lines available

References

• Original: J:336555 Scortegagna M, et al., Ubiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma. Cancer Res. 2023 Jun 15;83(12):2016-2033
• All: 1 reference(s)