Tg(ACTA2-SLC8A1*)DN2Twmt
Transgene Detail

Summary

• Symbol: Tg(ACTA2-SLC8A1*)DN2Twmt
• Name: transgene insertion DN2, Takahiro Iwamoto
• MGI ID: MGI:7514310
• Synonyms: Tg(hSMA-NCX1DN*trun)2
• Transgene: Tg(ACTA2-SLC8A1*)DN2Twmt Location: unknown
• Alliance: Tg(ACTA2-SLC8A1*)DN2Twmt page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Dominant negative, Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTA2-SLC8A1*)DN2Twmt expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  dog	SLC8A1 (475738)

• Tg(ACTA2-SLC8A1*)DN2Twmt expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  dog	ACTA2 (477587)

• Mutation details: The human promoter drives expression of the mutant dog cDNA of isoform 3 that is truncated at amino acid 601 and the mutation responsible for the amino acid substitutions serine with alanine at position 110 and glutamic acid with glutamine at position 113 S110A/E113Q). (J:104881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013
• All: 1 reference(s)