Tg(Rr241-Pkd2,-lacZ)3Hmd
Transgene Detail

Summary

• Symbol: Tg(Rr241-Pkd2,-lacZ)3Hmd
• Name: transgene insertion 3, Hiroshi Hamada
• MGI ID: MGI:7514228
• Synonyms: Foxa2NNE-hsp-Pkd2-IRES-LacZ, Tg(Foxa2mNE-hsp-Pkd2/lacZ)3Hmd, Tg(HFN3bmNE-hsp-Pkd2/lacZ)3Hmd
• Transgene: Tg(Rr241-Pkd2,-lacZ)3Hmd Location: unknown
• Alliance: Tg(Rr241-Pkd2,-lacZ)3Hmd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Rr241-Pkd2,-lacZ)3Hmd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pkd2 (MGI:1099818)

• Tg(Rr241-Pkd2,-lacZ)3Hmd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxa2 (MGI:1347476)

• Mutation details: The transgene contains a mouse Foxa2 node/notochordal specific enhancer, hsp promoter, E.coli LacZ gene, EMCV-derived protein synthesis initiation signal (IRES), and the mouse gene. (J:187958)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:187958 Yoshiba S, et al., Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2. Science. 2012 Oct 12;338(6104):226-31
• All: 1 reference(s)