Ythdc1^em#Sgao
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ythdc1^em#Sgao
• Name: YTH domain containing 1; endonuclease-mediated mutation, Shaorong Gao
• MGI ID: MGI:7514182
• Gene: Ythdc1 Location: Chr5:86952080-86984518 bp, + strand Genetic Position: Chr5, 43.56 cM
• Alliance: Ythdc1^em#Sgao page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to target exon 4. The pound sign indicates pooled mutations, consisting of large deletions encompassing exon 4. (J:309490)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ythdc1 Mutation: 53 strains or lines available

References

• Original: J:309490 Chen C, et al., Nuclear m(6)A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos. Protein Cell. 2021 Jun;12(6):455-474
• All: 1 reference(s)