Il17rb^tm1.1Sbn
Targeted Allele Detail

Summary

• Symbol: Il17rb^tm1.1Sbn
• Name: interleukin 17 receptor B; targeted mutation 1.1, Ulrich Siebenlist
• MGI ID: MGI:7514091
• Synonyms: Il17rb^flox
• Gene: Il17rb Location: Chr14:29718125-29730853 bp, - strand Genetic Position: Chr14, 18.39 cM
• Alliance: Il17rb^tm1.1Sbn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280768
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exons 2 and 3. FLP-mediated recombination in the germline resulted in the removal of the neomycin cassette, leaving the loxP sites flanking exons 2 and 3. (J:280768)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17rb Mutation: 40 strains or lines available

References

• Original: J:280768 Claudio E, et al., Cutting Edge: IL-25 Targets Dendritic Cells To Attract IL-9-Producing T Cells in Acute Allergic Lung Inflammation. J Immunol. 2015 Oct 15;195(8):3525-9
• All: 4 reference(s)