Anxa2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Anxa2^em1Cya
• Name: annexin A2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7513876
• Gene: Anxa2 Location: Chr9:69360978-69399074 bp, + strand Genetic Position: Chr9, 38.58 cM
• Alliance: Anxa2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-cas9 mediated recombination created a null allele. (J:338545)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Anxa2 Mutation: 53 strains or lines available

References

• Original: J:338545 Wang G, et al., The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression. Biochim Biophys Acta Mol Basis Dis. 2022 Apr 10;1868(8):166413
• All: 1 reference(s)