Tg(Mt1-Cd14*M14S)1Hgch
Transgene Detail

Summary

• Symbol: Tg(Mt1-Cd14*M14S)1Hgch
• Name: transgene insertion 1, Yasunori Higuchi
• MGI ID: MGI:7513872
• Transgene: Tg(Mt1-Cd14*M14S)1Hgch Location: unknown
• Alliance: Tg(Mt1-Cd14*M14S)1Hgch page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mt1-Cd14*M14S)1Hgch expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cd14 (MGI:88318)	Amino acid substitution M14S.

• Tg(Mt1-Cd14*M14S)1Hgch expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mt1 (MGI:97171)

• Mutation details: The transgene contains the mouse promoter driving expression of the house gene with the mutation responsible for the amino acid substitution of methionine with serine at position 14 (M15S). (J:57228)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:57228 Tamura Y, et al., CD14 transgenic mice expressing membrane and soluble forms: comparisons of levels of cytokines and lethalities in response to lipopolysaccharide between transgenic and non-transgenic mice. Int Immunol. 1999 Mar;11(3):333-9
• All: 1 reference(s)