Tg(DBH-PTS)41Csic
Transgene Detail

Summary

• Symbol: Tg(DBH-PTS)41Csic
• Name: transgene insertion 41, Chiho Sumi-Ichinose
• MGI ID: MGI:7513828
• Transgene: Tg(DBH-PTS)41Csic Location: unknown
• Alliance: Tg(DBH-PTS)41Csic page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(DBH-PTS)41Csic expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PTS (5805)

  Pts	(MGI:1338783)

• Tg(DBH-PTS)41Csic expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dbh (MGI:94864)

• Mutation details: This transgene consists of a 5.8 kb fragment containing the 5' promoter region of the human DBH gene, a rabbit beta-globin intron, a Kozak sequence, and a 441 bp cDNA encoding the human PTS gene. Five independent lines were generated. (J:102278)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:102278 Sumi-Ichinose C, et al., Genetically rescued tetrahydrobiopterin-depleted mice survive with hyperphenylalaninemia and region-specific monoaminergic abnormalities. J Neurochem. 2005 Nov;95(3):703-14
• All: 1 reference(s)