Lrp1^em1Wum
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lrp1^em1Wum
• Name: low density lipoprotein receptor-related protein 1; endonuclease-mediated mutation 1, Washington University School of Medicine
• MGI ID: MGI:7512763
• Synonyms: Lrp1^f
• Gene: Lrp1 Location: Chr10:127374030-127457017 bp, - strand Genetic Position: Chr10, 74.52 cM, cytoband B2-D1
• Alliance: Lrp1^em1Wum page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 14 was flanked by loxP sites via CRISPR/Cas9 technology. (J:338364)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrp1 Mutation: 212 strains or lines available

References

• Original: J:338364 Schwarz MM, et al., Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice. Sci Adv. 2023 Jul 14;9(28):eadh2264
• All: 1 reference(s)