Tg(Foxf1-tdTomato)912Lama
Transgene Detail

Summary

• Symbol: Tg(Foxf1-tdTomato)912Lama
• Name: transgene insertion 912, Vibha N Lama
• MGI ID: MGI:7511907
• Synonyms: Foxf1-tdTomato
• Transgene: Tg(Foxf1-tdTomato)912Lama Location: unknown Genetic Position: ChrUN, Syntenic
• Alliance: Tg(Foxf1-tdTomato)912Lama page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgenic construct contains the mouse Foxf1 gene (bacterial artificial chromosome clone, RP23-55G4) modified by BAC recombineering methods to insert the tdTomato coding sequence, a polyA sequence, an FRT-flanked PGK neo:gb2:kanamycin inserted into exon 1 of the Foxf1 gene. Transient flp infection removed the neo and kanamycin cassette. The final engineered BAC used for transgenic mouse production contained approximately 116,000 base pairs of DNA upstream from the tdTomato start site. The construct is followed by a chloramphenicol selection marker. The BAC clone does not include any other known genes. (J:338371)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:338371 Braeuer RR, et al., Transcription factor FOXF1 identifies compartmentally distinct mesenchymal cells with a role in lung allograft fibrogenesis. J Clin Invest. 2021 Nov 1;131(21)
• All: 1 reference(s)