Tg(Alb-Ppp1r15a)14Dron
Transgene Detail

Summary

• Symbol: Tg(Alb-Ppp1r15a)14Dron
• Name: transgene insertion 14, David Ron
• MGI ID: MGI:7511854
• Transgene: Tg(Alb-Ppp1r15a)14Dron Location: unknown
• Alliance: Tg(Alb-Ppp1r15a)14Dron page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Alb-Ppp1r15a)14Dron expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ppp1r15a (MGI:1927072)

• Tg(Alb-Ppp1r15a)14Dron expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Alb (MGI:87991)

• Mutation details: This transgene express a GADD34 C-terminal fragment (aa 292-590) from a liver-specific albumin promoter. Line 14 was generated. (J:137055)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:137055 Oyadomari S, et al., Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice. Cell Metab. 2008 Jun;7(6):520-32
• All: 1 reference(s)