Cmtr1^em1Embrp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cmtr1^em1Embrp
• Name: cap methyltransferase 1; endonuclease-mediated mutation 1, Ramesh S Pillai
• MGI ID: MGI:7511731
• Synonyms: Cmtr1^em1Rspi, Cmtr1^loxp
• Gene: Cmtr1 Location: Chr17:29879569-29924953 bp, + strand Genetic Position: Chr17, 15.43 cM
• Alliance: Cmtr1^em1Embrp page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was flanked by loxP sites via CRISPR/Cas9 technology. (J:338205)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cmtr1 Mutation: 47 strains or lines available

References

• Original: J:338205 Dohnalkova M, et al., Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility. Cell Rep. 2023 Jul 11;42(7):112786
• All: 1 reference(s)