Myh6em2(cre)Smoc
Endonuclease-mediated Allele Detail
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Symbol: |
Myh6em2(cre)Smoc |
Name: |
myosin, heavy polypeptide 6, cardiac muscle, alpha; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
MGI ID: |
MGI:7510097 |
Synonyms: |
Myh6-Cre, Myh6em(Cre)1Smoc |
Gene: |
Myh6 Location: Chr14:55179378-55204384 bp, - strand Genetic Position: Chr14, 28.01 cM
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Alliance: |
Myh6em2(cre)Smoc page
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Allele Type: |
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Endonuclease-mediated (Recombinase) |
Mutation: |
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Insertion
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Myh6em2(cre)Smoc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Myh6 (MGI:97255) |
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Mutation details: The CRISPR/Cas9 technology was used to insert the internal ribosome entry site (IRES)-Cre cassette, the woodchuck hepatitis virus posttranscriptional regulatory element (wpre), and a polyA sequence between the translational stop codon and the 3' UTR of the endogenous Myh6 gene.
(J:337240)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Myh6
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Myh6 Mutation: |
206 strains or lines available
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Original: |
J:337240 Huang X, et al., Generation and characterization of a Myh6-driven Cre knockin mouse line. Transgenic Res. 2021 Dec;30(6):821-835 |
All: |
2 reference(s) |
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