Tg(CAG-CAT,-Akt1/ERT,-IRES-lacZ)1Sato
Transgene Detail

Summary

• Symbol: Tg(CAG-CAT,-Akt1/ERT,-IRES-lacZ)1Sato
• Name: transgene insertion 1, Thomas N Sato
• MGI ID: MGI:7509519
• Synonyms: tmaAkt/Z
• Transgene: Tg(CAG-CAT,-Akt1/ERT,-IRES-lacZ)1Sato Location: unknown
• Alliance: Tg(CAG-CAT,-Akt1/ERT,-IRES-lacZ)1Sato page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(CAG-CAT,-Akt1/ERT,-IRES-lacZ)1Sato expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Akt1 (MGI:87986)	Expresses a Akt protein kinase/mutant murine estrogen receptor (ER) fusion protein with a hemagglutinin epitope tag

• Tg(CAG-CAT,-Akt1/ERT,-IRES-lacZ)1Sato expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: The transgene construct contains the CAG promotor (beta-actin chicken promoter and CMV enhancer), a chloramphenicol (CAT) sequence flanked by loxP sequences followed by a mouse Akt protein kinase/mutant murine estrogen receptor (ER) fusion protein, a hemagglutinin epitope tag, and IRESLacZ. (J:82685)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:82685 Kroll J, et al., Versatile inducible activation system of Akt/PKB signaling pathway in mice. Genesis. 2003 Mar;35(3):160-3
• All: 7 reference(s)