Tg(CD2-Ahr*)KKno
Transgene Detail

Summary

• Symbol: Tg(CD2-Ahr*)KKno
• Name: transgene insertion K, Keiko Nohara
• MGI ID: MGI:7507495
• Synonyms: Tg(hCD2-CA-AhR)K
• Transgene: Tg(CD2-Ahr*)KKno Location: unknown
• Alliance: Tg(CD2-Ahr*)KKno page

Transgene origin

• Strain of Origin: C57BL/6J x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD2-Ahr*)KKno expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ahr (MGI:105043)

• Tg(CD2-Ahr*)KKno expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CD2 (914)

  Cd2	(MGI:88320)

• Mutation details: The transgene contains the human CD2 promoter driving expression of a constitutively active mouse aryl hydrocarbon receptor. (J:97720)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:97720 Nohara K, et al., Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes. J Immunol. 2005 Mar 1;174(5):2770-7
• All: 1 reference(s)