Angptl2^tm1Zhej
Targeted Allele Detail

Summary

• Symbol: Angptl2^tm1Zhej
• Name: angiopoietin-like 2; targeted mutation 1, Junke Zheng
• MGI ID: MGI:7506870
• Synonyms: Angptl2^fl
• Gene: Angptl2 Location: Chr2:33106081-33137729 bp, + strand Genetic Position: Chr2, 22.36 cM
• Alliance: Angptl2^tm1Zhej page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:337802
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. (J:337802)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl2 Mutation: 35 strains or lines available

References

• Original: J:337802 Yu Z, et al., Endothelial cell-derived angiopoietin-like protein 2 supports hematopoietic stem cell activities in bone marrow niches. Blood. 2022 Mar 10;139(10):1529-1540
• All: 1 reference(s)