Nsun6^em1Fang
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nsun6^em1Fang
• Name: NOL1/NOP2/Sun domain family member 6; endonuclease-mediated mutation 1, Liang Fang
• MGI ID: MGI:7506239
• Gene: Nsun6 Location: Chr2:14999942-15059880 bp, - strand Genetic Position: Chr2, 10.94 cM, cytoband A2
• Alliance: Nsun6^em1Fang page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted exons 3 and 4. Western blot analysis confirmed absence of protein in homozygotes. (J:337561)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nsun6 Mutation: 28 strains or lines available

References

• Original: J:337561 Wang W, et al., A Cross-Tissue Investigation of Molecular Targets and Physiological Functions of Nsun6 Using Knockout Mice. Int J Mol Sci. 2022 Jun 13;23(12)
• All: 1 reference(s)