Tgfb1^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Tgfb1^tm1Smoc
• Name: transforming growth factor, beta 1; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7505608
• Synonyms: TGF-Beta1^flox
• Gene: Tgfb1 Location: Chr7:25386427-25404502 bp, + strand Genetic Position: Chr7, 13.98 cM
• Alliance: Tgfb1^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303641
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites. An FRT-flanked neomycin selection cassette was inserted downstream of the floxed exon. (J:303641)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgfb1 Mutation: 34 strains or lines available

References

• Original: J:303641 Song W, et al., Loss of transforming growth factor-beta1 in epithelium cells affects enamel formation in mice. Arch Oral Biol. 2018 Dec;96:146-154
• All: 3 reference(s)