Saa1^tm2Itl
Targeted Allele Detail

Summary

• Symbol: Saa1^tm2Itl
• Name: serum amyloid A 1; targeted mutation 2, inGenious Targeting Laboratory
• MGI ID: MGI:7496056
• Synonyms: SAA1.1KO
• Gene: Saa1 Location: Chr7:46389921-46392404 bp, - strand Genetic Position: Chr7, 30.54 cM
• Alliance: Saa1^tm2Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233759
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP/FRT floxed neo cassette replaced a 5.3 kb genome fragment including exons 2-4 and the translation start codon. (J:233759)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Saa1 Mutation: 11 strains or lines available

References

• Original: J:233759 Kim MH, et al., Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice. J Lipid Res. 2016 Jun;57(6):969-79
• All: 1 reference(s)