Ikzf2^em1Zyliu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ikzf2^em1Zyliu
• Name: IKAROS family zinc finger 2; endonuclease-mediated mutation 1, Zhiyong Liu
• MGI ID: MGI:7495783
• Synonyms: Ikzf2^V5
• Gene: Ikzf2 Location: Chr1:69570373-69726404 bp, - strand Genetic Position: Chr1, 34.9 cM
• Alliance: Ikzf2^em1Zyliu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Reporter)
• Mutation: Insertion
• Mutation details: Plasmids encoding a sgRNA (5'- AGGGGAGCACACATTCCACT-3') were designed to fuse a 3xV5 epitope tag and a P2A self-cleaving peptide sequence (P2A)-tdTomato cassette close to the stop codon. Insertion of this reporter cassette does not affect endogenous gene expression. (J:337553)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ikzf2 Mutation: 44 strains or lines available

References

• Original: J:337553 Bi Z, et al., Development and transdifferentiation into inner hair cells require Tbx2. Natl Sci Rev. 2022 Dec;9(12):nwac156
• All: 2 reference(s)