Gucy2c^em1Sawn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gucy2c^em1Sawn
• Name: guanylate cyclase 2c; endonuclease-mediated mutation 1, Scott Arthur Waldman
• MGI ID: MGI:7495610
• Synonyms: Gucy2c^fl
• Gene: Gucy2c Location: Chr6:136674282-136758740 bp, - strand Genetic Position: Chr6, 66.67 cM
• Alliance: Gucy2c^em1Sawn page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a floxed allele. No molecular details were provided. (J:337523)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gucy2c Mutation: 69 strains or lines available

References

• Original: J:337523 Barton JR, et al., Intestinal neuropod cell GUCY2C regulates visceral pain. J Clin Invest. 2023 Feb 15;133(4)
• All: 1 reference(s)