Tg(IghmGD2,IgkGD2)1Rin
Transgene Detail

Summary

• Symbol: Tg(IghmGD2,IgkGD2)1Rin
• Name: transgene insertion 1, The Tokyo Metropolitan Institute of Medical Science
• MGI ID: MGI:7495594
• Synonyms: Tg(GMB7)1Rin
• Transgene: Tg(IghmGD2,IgkGD2)1Rin Location: unknown
• Alliance: Tg(IghmGD2,IgkGD2)1Rin page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains the variable region rearrangement against ganglioside GD2 introduced into IgM heavy chain cassette (V167 mu) and IgM light chain cassette (pMM222). (J:337521)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:337521 Kawashima I, et al., Expansion of natural killer cells in mice transgenic for IgM antibody to ganglioside GD2: demonstration of prolonged survival after challenge with syngeneic tumor cells. Int J Oncol. 2003;23(2):381-8
• All: 1 reference(s)