Casp7^tm1Acau
Targeted Allele Detail

Summary

• Symbol: Casp7^tm1Acau
• Name: caspase 7; targeted mutation 1, Anje Cauwels
• MGI ID: MGI:7495522
• Synonyms: Casp7^fl, Caspase-7^flox
• Gene: Casp7 Location: Chr19:56385561-56430776 bp, + strand Genetic Position: Chr19, 51.84 cM
• Alliance: Casp7^tm1Acau page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179279
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo cassette was inserted downstream of exon 5 via homologous recombination. (J:179279)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Casp7 Mutation: 17 strains or lines available

References

• Original: J:179279 Duprez L, et al., RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome. Immunity. 2011 Dec 23;35(6):908-18
• All: 2 reference(s)